Phospho acc
WebAcetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. …
Phospho acc
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WebIncreased expression of phospho-acetyl-CoA carboxylase protein is an independent prognostic factor for human gastric cancer without lymph node metastasis. Upregulation … WebAcetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the …
WebThe Phospho-Acetyl-CoA Carboxylase (Ser79) Antibody has been validated for the following applications: Precipitation, Immunohistochemistry, Immunohistochemistry - fixed, Immunoprecipitation, and Western Blot. Phospho-Acetyl-CoA Carboxylase (Ser79) Antibody detects endogenous levels of ACC only when phosphorylated at serine 79. WebSep 13, 2024 · DSG treatment upregulated expression of lipolysis proteins, including phospho-AMP activated protein kinase (p-AMPK), phospho-acetyl-coA carboxylase (p-ACC) and carnitine acyl transferase 1A (CPT-1A), and inhibited expression of lipid synthesis-related proteins, including sterol regulatory element-binding protein 1c (SREBP-1c) and …
WebMay 17, 2013 · AMPK activation was reflected by phosphorylation of AMPKα (Thr 172) and ACC (Acetyl-CoA Carboxylase, Ser 79) , while MAPK activation was demonstrated by phosphorylation of JNK, ERK and p38 ... phospho- and non-phospho- AMPK, ACC and eIF2α were detected as described above (E); (B) ... WebMar 21, 2024 · Furthermore, we also used a phospho-ACC (Ser79) cellular HTRF assay kit (96-well plate reader assay format), which we optimized for this cell line to measure activation of AMPK in a linear range across a number of doses of compounds, including A-769662 and an AMP mimetic prodrug, 5-aminoimidazole-4-carboxamide riboside (AICAR) …
WebAcetyl-CoA Carboxylase. ACC is the first committed step in the pathway of fatty acid synthesis, and is also subject to regulation by the three mechanisms (Figures 2 and 5). …
WebAn ACC mouse antibody has been coated onto the microwells. After incubation with cell lysates, ACC (phospho and nonphospho) is captured by the coated antibody. Following extensive washing, an ACC rabbit detection antibody is added to … first sacrament of godWebACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and ... first sack of rome gaulsWebSep 1, 2024 · The Phospho-Acetyl-CoA Carboxylase (Ser79) (D7D11) Rabbit mAb Antibody from Cell Signaling Technology is a Rabbit Monoclonal antibody to ACACA, and ACACB. This antibody recognizes Human, Mouse, and Rat antigen. The Phospho-Acetyl-CoA Carboxylase (Ser79) (D7D11) Rabbit mAb Antibody has been validated for the following applications: … first sacred war kirrhaWebAug 1, 2024 · In contrast to wild-type (WT) MEF cells, AICAR treatment did not induce AMPK activation signal phospho-AMPKα (Thr172) and substrate signal phospho-ACC (Thr79) in the three KO cell lines, further suggesting the loss of AMPKα1 and α2 kinase activity (Figure 1 C). Besides, we extracted genomic DNA from individual cell lines for sequencing and ... first sacrament of the catholic churchWebApr 11, 2024 · All phospho-mutant mice had a C57BL/6 genetic background. All mice were bred in a specific-pathogen-free (SPF) environment. All animal experiments were approved by the Animal Ethics Committee of Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China (Nos. HKDL-2016-221 and SH9H-2024-A1-1). first sacramentWebphos·pho·rus. ( fos'fŏr-ŭs) A nonmetallic chemical element, occurring extensively in nature; the elemental form is extremely poisonous, causing intense inflammation and fatty … first safe country ruleWebAug 1, 2006 · The phosphorylation of AMPK and its downstream target, ACC, was assessed by using immunoblots with phospho-Thr-172 AMPKα (pAMPK) and phospho-Ser-79 ACC1 (Ser221 ACC2; pACC) antibodies. The levels of phosphorylated AMPK and the sum of phosphorylated ACC1 and ACC2 were normalized to endogenous AMPKα levels and … camouflage attire