Cisplatin platinum based

Author: wunh

August undefined, 2024

WebMar 20, 2024 · Platinum-based anticancer drugs, including cisplatin, carboplatin, oxaliplatin, nedaplatin, and lobaplatin, are heavily applied in chemotherapy regimens. However, the intrinsic or acquired resistance severely limit the clinical application of platinum-based treatment. The underlying mechanisms are incredibly complicated. WebJun 6, 2024 · Cisplatin-based concurrent chemoradiotherapy has been identified as the primary and standard treatment for locally advanced nasopharyngeal carcinoma (NPC). However, the side effects of cisplatin affect the compliance to therapy. Thus, the search for a platinum-based substitute for NPC has always been a research focus.

A source of hope for platinum-resistant ovarian cancer?

WebFeb 16, 2024 · Common side effects of cisplatin may include: hearing problems; kidney problems; numbness or tingling; nausea, vomiting; or. bone marrow suppression. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. WebCisplatin, a class of platinum-containing anticancer drugs for the treatment of solid tumors, is a substrate of OCT2 and MATE1/MATE2-K. OCT2 is expressed in the basolateral membrane of proximal tubules and mediates the transport of cisplatin from the blood to proximal tubule cells. how fast does an ipad charge

Comparison of the second-line treatments for patients with small …

WebMar 23, 2024 · For nearly five decades, cisplatin has played an important role as a standard chemotherapeutic agent and been prescribed to 10-20% of all cancer patients. … WebJun 13, 2005 · Cisplatin, cisplatinum or cis-diamminedichloroplatinum (II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas and germ cell tumors. WebApr 10, 2024 · Triple-negative breast cancer (TNBC) is one of the most aggressive forms of breast cancer and constitutes 10–20% of all breast cancer cases. Even though platinum-based drugs such as cisplatin and carboplatin are effective in TNBC patients, their toxicity and development of cancer drug resistance often hamper their clinical use. … how fast does an legacy maple tree grow

Electrolyte disorders with platinum-based …

Cisplatin nephrotoxicity - UpToDate

WebSep 1, 2024 · Cisplatin for injection, USP, a platinum-based drug for intravenous use, is a white to light yellow lyophilized powder. Each vial of Cisplatin for injection, USP … WebJul 22, 2024 · Cellular toxicity — Cisplatin (cis-diamminedichloroplatinum II [CDDP]), a platinum compound that is predominantly eliminated through renal clearance. Inside … how fast does an oak tree growWebCisplatin, a chemotherapy drug, is best known for curing testicular cancer. It is also used in the treatment of a wide range of other cancers, including lung, bladder, cervical, and ovarian cancers. Cisplatin and other similar … how fast does an olympic luge go

"WebCross-reactivity between platinum-based antineoplastic agents reported; cases of severe hypersensitivity reactions have recurred after rechallenging patients with a different platinum agent; Ototoxicity. Cisplatin for … " - Cisplatin platinum based

Cisplatin platinum based

The side effects of platinum-based chemotherapy drugs: …

WebCisplatin definition, a platinum-containing white powder, PtCl2H6N2, used to treat ovarian carcinoma and other cancers. See more. WebPlatinum-based anticancer drugs, such as cisplatin, are standard chemotherapeutic agents in ovarian cancer therapy. Citation 39 , Citation 40 This class of drugs can penetrate the nucleus of cancer cells and form adducts with genomic or mitochondrial DNA to block the production of DNA, mRNA, and proteins, arrest DNA replication, and activate ...

Did you know?

WebFeb 1, 2024 · Cisplatin injection is used to treat advanced cancer of the bladder, ovaries, or testicles. Cisplatin is an antineoplastic agent (cancer medicine). It interferes with the growth of cancer cells, which are eventually destroyed by the body. This medicine is to be given only by or under the direct supervision of a doctor. WebMar 29, 2024 · Reviewed on 3/29/2024. Cisplatin: An anticancer drug that belongs to the family of drugs called platinum compounds. Cisplatin is used in the treatment of a wide …

WebPlatinum compounds, such as carboplatin and cisplatin, are commonly used for the treatment of endometrial, ovarian and testicular cancer. Conflicting studies have been reported with regards to the sensitivity of MMR deficient tumors cells to platinum treatment. WebOct 5, 2014 · Cisplatin and carboplatin are two of the most common types of platinum based treatments used in SCLC chemotherapy (Go and Adjei, 1999). In clinical trials, …

WebJan 23, 2024 · Effective and well tolerated treatment for platinum-resistant ovarian cancer remains a substantial unmet need. Despite the introduction of targeted and immunological therapies for its management, platinum-based chemotherapy with carboplatin or cisplatin remains the backbone of treatment. WebApr 10, 2024 · Triple-negative breast cancer (TNBC) is one of the most aggressive forms of breast cancer and constitutes 10–20% of all breast cancer cases. Even though platinum …

WebA capillary gas chromatographic method is described for the determination of cisplatin based on the complexation of platinum (II) with bis (isovalerylacetone) ethylenediimine (H_2IVA_2en) and extract

WebNov 7, 2024 · Platinum compounds, i.e. cisplatin ( [Pt (NH 3) 2 Cl 2 ]) or carboplatin ( [Pt (C 6 H 6 O 4 ) (NH 3) 2 ]) are among the most important agents for chemotherapeutic treatment of solid cancers. As... high definition television rating high definition television comparisonWebCisplatin (cis-diaminedichloroplatinum [II]) is a platinum-based chemotherapy drug that has been FDA-approved for treatment of a variety of cancers including sarcomas, small … high definition television purchaseWebSep 5, 2011 · Platinum-based drugs, and in particular cis -diamminedichloroplatinum (II) (best known as cisplatin), are employed for the treatment of a wide array of solid malignancies, including... how fast does a nissan altima goWebPlatinum-based regimens, such as cisplatin/carboplatin plus etoposide/irinotecan are recommended therapy for SCLC as first-line chemotherapy treatment . Patients with SCLC are commonly categorized into sensitive or refractory relapse based on whether they responded to first-line chemotherapy. A sensitive relapse is defined as patients who ... high definition televisionsWebThe platinum-based drugs cisplatin, carboplatin and oxaliplatin are regularly prescribed in the treatment of cancer and while they are effective, their use is limited by their severe, … how fast does annual ryegrass germinateWebPlatinum-based agents are important drugs or drug candidates for cancer chemotherapy. Traditional platinum drugs including the globally approved cisplatin, carboplatin and oxaliplatin are neutral platinum (II) complexes with two amine ligands and two additional ligands that can be aquated for further binding with DNA. how fast does an object fall