WebNursing Implications Assessment & Drug Effects Lab tests: Obtain total and differential leukocyte counts before each dose is administered. Baseline and periodic checks of Hct and liver and kidney function are also advised. Use protective isolation of patient during leukopenic period (WBC 3500/mm3). WebIntraarterial cisplatin infusion: nursing implications Author N M Leahy Abstract Patients diagnosed with malignant intracranial tumors have limited chemotherapeutic options. …

Cisplatin (Intravenous Route) Side Effects - Mayo Clinic

Webwhat are the indications for cisplatin? - testicular cancer - ovarian cancer - lung cancer - head/neck cancer what is the dose-limiting toxicity for cisplatin? - kidney injury what are the other major toxicities associated with cisplatin? - tinnitus/hearing loss - peripheral neuropathy - bone marrow suppression - n/v Assessment & Drug Effects 1. Obtain baseline ECG and cardiac monitoring during induction therapy because of possible myocarditis or focal irritability. 2. Lab tests: The following tests should be done beforeinitiating every course of therapy and repeated each week during treatment period: serum uric acid, … See more A heavy metal complex with platinum as central atom surrounded by 2 chloride atoms and 2 ammonia molecules in the cis chemical position. Biochemical properties similar to those of bifunctional alkylating agents. Produces … See more Established combination therapy (cisplatin, vinblastine, bleomycin) in patient with metastatic testicular tumors and with doxorubicin for metastatic ovarian tumors following appropriate … See more Cell cycle-nonspecific, i.e., effective throughout the entire cell life cycle. Carcinogenicity has not been fully studied, but other compounds with similar action mechanisms and mutogenicity have been studied. See more History of hypersensitivity to cisplatin or other platinum-containing compounds; impaired renal function; myelosuppression; impaired hearing; history of gout and … See more determine priority of risks

Cisplatin (Intravenous Route) Precautions - Mayo Clinic

http://www.robholland.com/Nursing/Drug_Guide/data/monographframes/C085.html WebCisplatin is a platinum-based agent whose nephrotoxicity is thought related to the chloride in the cis position. Cisplatin gains entry into tubular cells via uptake by the OCT-2 … determine primary and secondary insurance